modafinil will increase the degree or impact of clobazam by impacting hepatic enzyme CYP2C19 metabolism. Use Caution/Monitor. Dosage adjustment can be necessary; CYP2C19 inhibitors may well end in enhanced publicity to N-desmethylclobazam (Energetic metabolite). modafinil will lower the extent or effect of norgestrel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. https://modafinil21087.prublogger.com/25880344/facts-about-modafinil-revealed