Adaptive clinical trials use existing knowledge to design the trial, and after that use interim benefits to modify the trial as it proceeds. Modifications consist of dosage, sample size, drug undergoing trial, patient selection standards and "cocktail" blend.[39] Adaptive trials generally use a Bayesian experimental design to assess the trial's https://sign-up-for-a-clinical-st24679.isblog.net/the-basic-principles-of-clinical-trials-participant-application-43788826