The objective of this review was to research the consequences of αvβthree-integrin inhibitor to the proliferation and apoptosis of melanoma cells, along with the sensitivity of immune checkpoint inhibitors. Our final results uncovered that cilengitide inhibited proliferation and enhanced apoptosis in melanoma cells in vitro. Preclinical data have demonstrated fenebrutinib https://friedrichn420ekp3.wikipublicity.com/user