Hop into a moto-taxi and if they don't know 'Tambopata Hostel', or 'avenida 26 de deciembre', just ask for the Plaza de Armas (primary town square); continue previous the leading square on the appropriate hand side, and on reaching the top corner ask the motive force to turn ideal (derecha) https://travelsia.com/puerto-maldonado-airport-the-amazon-awaits