Pentobarbital boosts toxicity of buprenorphine, prolonged-performing injection by pharmacodynamic synergism. Modify Therapy/Observe Closely. Coadministration of buprenorphine and benzodiazepines or other CNS depressants boosts threat of adverse reactions including overdose, respiratory despair, and Dying. Cessation of benzodiazepines or other CNS depressants is desired typically. pent... https://caleba210rgu8.wikipublicist.com/user